Nurse Practitioners Salary in Mississippi

Nurse practitioners in Mississippi earn the most in Gulfport (average $129,270 a year) and the least in Hattiesburg ($119,160), across the 3 Mississippi metro areas we cover. Statewide, BLS puts the nurse practitioners average at $125,340 and the median at $124,730 for 4,690 workers. The U.S. average for this job is $137,300.

Nurse Practitioners average salary by city in Mississippi

Gulfport$129,270
Jackson$126,930
Hattiesburg$119,160

Pay, take-home pay and cost of living

City	Average	Median	25th pct.	Take-home*	Cost of living
Gulfport	$129,270	$128,150	$110,670	$95,183	90
Jackson	$126,930	$124,730	$109,360	$93,677	89
Hattiesburg	$119,160	$113,300	$104,990	$88,625	88

*Average salary after federal and state taxes for a single filer. Cost of living: BEA price parity, U.S. = 100.

Nurse Practitioners salary in other states

Nurse Practitioners salary by city and state

More about pay in Mississippi

Sources and how to read this page

Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1171.
U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.

Read the full methodology. Spotted an error? Tell us.